telomerase and systems controlling their activity have been of great attention. there are controversies regarding the role of the alternative splicing forms of the human telomerase reverse transcriptase (htert), the catalytic subunit of telomerase. therefore, the correlation between telomerase enzyme activity, the abundance of alternatively spliced variants of htert and doubling time of a serie...

Background and Aim: Recently, several studies have indicated that the central nervous system has the capacity for endogenous repair. But, the proliferation capacity of endogenous neural stem cells (NSCs) isn’t sufficient for the treatment of neurodegenerative diseases. So, it sounds that stimulation of endogenous NSC proliferation is essential for neuroregeneration. The aim of this study ...

Much public discussion about foreign aid has focused on whether and how to increase its quantity. But recently aid quality has come to the fore, by which is meant the efficiency of the aid delivery process. This paper focuses on one process problem, the proliferation of aid projects and the associated administrative burden for recipients. It models aid delivery as a set of production activities...

background: bone marrow derived mesenchymal stem cells (mscs) are a population of multipotent progenitors which have the capacity of proliferation and differentiation into mesenchymal lineage cells. hypoxia could promote the proliferation of mscs. micro-rnas are endogenous rnas that can play an important role in some processes such as proliferation and differentiation. mir-210 could help for be...

The hippocampal dentate gyrus maintains its capacity to generate new neurons throughout life. In animal models, hippocampal neurogenesis is increased by cognitive tasks, and experimental ablation of neurogenesis disrupts specific modalities of learning and memory. In humans, the impact of neurogenesis on cognition remains unclear. Here, we assessed the neurogenic potential in the human hippocam...

In recent years, considerable advances have been made in the field of regenerative medicine. Unlikeembryonic stem cells, which pose the problems of ethical concerns and cause severe immunological reactions as well as neoplasma formation after transplantation, umbilical cord blood is a primitive source ofmesenchymal stem cells that covers the benefits of both embryonic and adult stem cells. It h...

in recent years, considerable advances have been made in the field of regenerative medicine. unlikeembryonic stem cells, which pose the problems of ethical concerns and cause severe immunological reactions as well as neoplasma formation after transplantation, umbilical cord blood is a primitive source ofmesenchymal stem cells that covers the benefits of both embryonic and adult stem cells. it h...

background: human dental stem cells have high proliferative potential for self-renewal that is important to the regenerative capacity of the tissue. objective: the aim was to isolate human dental pulp stem cells (dpsc), periodontal ligament stem cells (pdlsc) and periapical follicle stem cells (pafsc) for their potential role in tissue regeneration. materials and methods: in this experimental s...